Ancient Origin of Glycosyl Hydrolase Family 9 Cellulase Genes

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Ancient origin of glycosyl hydrolase family 9 cellulase genes.

While it is widely accepted that most animals (Metazoa) do not have endogenous cellulases, relying instead on intestinal symbionts for cellulose digestion, the glycosyl hydrolase family 9 (GHF9) cellulases found in the genomes of termites, abalone, and sea squirts could be an exception. Using information from expressed sequence tags, we show that GHF9 genes (subgroup E2) are widespread in Metaz...

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Defining Cellulase in the Glycosyl Hydrolase Family 48 Sequence, Structure, and Evolution of Cellulases in the Glycoside Hydrolase Family 48

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Background: Cellulases are non-homologous isofunctional enzymes, which prevents their unambiguous identification in genomic datasets. Results: Cellulases from glycoside hydrolase family 48 have distinct evolutionarily conserved sequence and structural features. Conclusion: Conserved sequence/structure features can be used to differentiate cellulases from non-cellulases in genomic datasets. Sign...

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ژورنال

عنوان ژورنال: Molecular Biology and Evolution

سال: 2005

ISSN: 1537-1719,0737-4038

DOI: 10.1093/molbev/msi107