منابع مشابه
Ancient DNA research goes nuclear
136 biotech and life sciences worldwide as part of a larger project to map human technological development (Fig 1). “Maps can help answer or at least address a number of key questions,” said Hoffman. “Where around the world is biotech really happening or beginning to happen? How important is economic geography now that the life sciences are spilling out of university, governmental and industria...
متن کاملNuclear DNA typing from ancient teeth.
Because of the adverse effects that diagenesis exert on ancient skeletal remains, DNA from these samples is often compromised to the point where genetic typing can be challenging. Nevertheless, robust and reliable methods are currently available to allow successful genotyping of ancient specimens. Here we report nuclear DNA-based methods and typing strategies used to analyze 2 human skeletons f...
متن کاملBAF goes nuclear
Two channels, one program he biophysical and structural characteristics of chloride ion channels have been studied extensively, but little is known about the molecular regulation and signaling pathways associated with these highly conserved proteins. Rutledge et al. (page 435) analyzed the activation of the CLH-3 chloride ion channel in C. elegans during meioitic cell cycle progression and in r...
متن کاملmiRNA goes nuclear
microRNAs (miRNAs), defined as 21-24 nucleotide non-coding RNAs, are important regulators of gene expression. Initially, the functions of miRNAs were recognized as post-transcriptional regulators on mRNAs that result in mRNA degradation and/or translational repression. It is becoming evident that miRNAs are not only restricted to function in the cytoplasm, they can also regulate gene expression...
متن کاملβ-Arrestin Goes Nuclear
Arrestins are a family of scaffolding proteins that are closely associated with the function of seven transmembrane domain G protein-coupled receptors (GPCRs). In mammals, two members of the arrestin family, the visual arrestins, are restricted to photoreceptor cells, whereas two others, β-arrestin 1 and β-arrestin 2, are expressed ubiquitously. These proteins promote the internalization and de...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2006
ISSN: 1469-221X,1469-3178
DOI: 10.1038/sj.embor.7400634