منابع مشابه
Ancient DNA Comes of Age
Feature T he study of genetic material from ancient specimens was, in its early years, dominated by a race to sequence DNA from extinct species like the dodo and the woolly mammoth. Now that the supply of these crowd-pleasing curiosities has run dry, scientists are starting to ask new questions of ancient DNA (aDNA) that are revealing how the genetic make-up of prehistoric populations changed t...
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Glyceroneogenesis is a generally ignored metabolic pathway that occurs in adipose tissues and liver of mammalian species. This short review highlights a series of recent discoveries showing that glyceroneogenesis is important in lipid homeostasis.
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Introduction Ageing of the immune system (immunosenescence) contributes to the increased susceptibility of the elderly to infectious disease and to the poor outcome of vaccination. Defence against pathogens is compromised mainly because of changes in adaptive immunity mediated by T and B lymphocytes; however, all components of the immune system are affected (Fig 1). Dissecting the crucial alter...
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The posttranslational modification of proteins by methylglyoxal, a highly reactive compound derived from glycolysis, may contribute to aging, diabetes, and other disorders. In this issue of Cell, Brownlee and colleagues (Yao et al., 2006) demonstrate a specific mechanism by which methylglyoxal modifies a transcriptional corepressor to enhance gene expression.
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Since its first technology qualification in 1996 in IBM’s Advanced Semiconductor Technology Center (ASTC), Hopewell Junction, NY, silicon germanium (SiGe) has become the darling of the chip world, with new product and development agreement announcements made on nearly a daily basis. In this paper, we update progress made in SiGe since our 1Q97 IBM MicroNews article [1], tracing a number of busi...
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ژورنال
عنوان ژورنال: PLoS Biology
سال: 2005
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.0030056