ANCA-positive Churg-Strauss syndrome with renal failure

ANCA-positive Churg-Strauss syndrome with renal failure.

Churg–Strauss syndrome was described in 1951 as a granulomatous variant of polyarteritis nodosa with eosinophilic tissue infiltration [1]. The clinical presentation corresponds to that of a systemic vasculitis involving one or more extrapulmonary organs with asthma and peripheral blood eosinophilia in excess of 1.5×109/l [2 ]. Our 56-year-old patient was primarily treated for spastic bronchitis...

Reversible acute renal failure due to Churg-Strauss syndrome.

Renal disease in Churg-Strauss syndrome is generally thought to be benign in nature, thereby distinguishing this rare condition from other necrotizing vasculitides. We report a case in which acute renal failure developed during the aggressive vasculitic phase of the illness requiring dialysis therapy. After one week of daily haemodialysis treatment the patient had become encephalopathic associa...

Renal involvement in Churg-Strauss syndrome.

Churg-Strauss syndrome is part of the spectrum of systemic vasculitis, but can be distinguished from the other necrotising vasculitides on the basis of clinical and histological criteria. Renal involvement is not regarded as a prominent feature and is generally mild. We report a series of 19 patients with Churg-Strauss syndrome referred to the Hammersmith Hospital between 1976 and 1986. Renal i...

Churg-Strauss syndrome.

Churg-strauss syndrome.

First described in 1951 as an allergic and granulomatous angiitis, Churg-Strauss syndrome (CSS) is a small-vessel vasculitis. Mean age at the time of diagnosis is approximately 50 years, with a sex ratio around 1. Asthma is the central feature of CSS and precedes the systemic manifestations in almost all cases, whereas 70% of the patients have maxillary sinusitis, allergic rhinitis, and/or sinu...