Anaplastic thyroid carcinoma: Current diagnosis and treatment

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Anaplastic thyroid carcinoma: current diagnosis and treatment.

BACKGROUND Anaplastic thyroid carcinoma (ATC), accounting for 5% to 15% of primary malignant thyroid neoplasms, is one of the most aggressive solid tumors in humans. Generally, it is rapidly fatal, with a mean survival of six months after diagnosis. Multimodality treatment with surgery and/or external beam radiotherapy and chemotherapy are of fundamental importance for local control of disease ...

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Diagnosis and Treatment of Anaplastic Thyroid Carcinoma

Anaplastic thyroid carcinoma (ATC) is a poorly differentiated thyroid cancer. It cannot uptake iodine or synthesis thyroglobulin. The incidence is low; about 2% 5% of thyroid cancer. The peak age incidence is 60 70 years and it is more common in females (55% 77% of all patients). In recent years, the incidence has declined; however, it may be higher in areas of endemic goiter. ATC may occur wit...

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Anaplastic Thyroid Carcinoma: Molecular Tools for Diagnosis and Therapy

1 Institute of Molecular Biology and Genetics (IBGM), Valladolid University (Uva), Spanish Research Council (CSIC), C/ Sanz y Fores s/n, 47003 Valladolid, Spain 2Scuola di Medicina e Chirurgia, Università di Bologna, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Anatomia Patologica, Ospedale Bellaria Via Altura 3, 40139 Bologna, Italy 3Dipartimento di Scienze Motorie e del...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2000

ISSN: 0923-7534

DOI: 10.1023/a:1008322002520