منابع مشابه
Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.
BACKGROUND Recent advances that have been made in diagnostic imaging, surgical technique, chemotherapy, molecular biology, and prediction of therapeutic response could have potential impact on the optimal diagnosis and treatment of patients with brain tumors, especially those with oligodendrogliomas. In this article, the topic of oligodendroglioma and anaplastic oligodendroglioma is reviewed, h...
متن کاملSurvey of treatment recommendations for anaplastic oligodendroglioma.
Anaplastic oligodendroglioma is a malignant brain tumor uniquely sensitive to treatment with both chemotherapy and radiotherapy. There are few prospective clinical trials for newly diagnosed patients and multiple approaches to the treatment of these patients. This study explored the recommended treatment offered by experts in neuro-oncology. A Web-based survey was developed and distributed to 8...
متن کاملTCF12 is mutated in anaplastic oligodendroglioma
Anaplastic oligodendroglioma (AO) are rare primary brain tumours that are generally incurable, with heterogeneous prognosis and few treatment targets identified. Most oligodendrogliomas have chromosomes 1p/19q co-deletion and an IDH mutation. Here we analysed 51 AO by whole-exome sequencing, identifying previously reported frequent somatic mutations in CIC and FUBP1. We also identified recurren...
متن کاملBevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma.
BACKGROUND A retrospective evaluation of single agent bevacizumab was carried out in adults with recurrent alkylator-refractory 1p19q codeleted anaplastic oligodendrogliomas (AO) with an objective of determining progression-free survival (PFS). There is no standard therapy for alkylator-resistant AO, and hence a need exists for new therapies. METHODS Twenty-two patients aged 24 to 60 years wi...
متن کاملPsoriatic Arthritis during Treatment with Bevacizumab for Anaplastic Oligodendroglioma
Bevacizumab is a recombinant humanised monoclonal antibody directed against the vascular endothelial growth factor (VEGF). The drug, alone or in combination with other anticancer agents, has been shown to be effective against several types of neoplasms. We report a case of a woman with a history of severe psoriasis who developed psoriatic arthritis during a course of bevacizumab, which was admi...
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ژورنال
عنوان ژورنال: Current Treatment Options in Neurology
سال: 2008
ISSN: 1092-8480,1534-3138
DOI: 10.1007/s11940-008-0032-y