Anaphylaxis to oral misoprostol in a term pregnant patient who is non-allergic to vaginal misoprostol-a case report

Misoprostol (PGE1) is a drug that very commonly used in obstetrics for labour induction. Apart from its side effect of causing congenital malformations offspring users who have unsuccessfully it as an abortifacient, considered safe with few effects. We here report severe hypersensitivity reaction to misoprostol 33-year-old term pregnant patient non-allergic vaginal misoprostol. The developed anaphylactic features like swelling lips, low voice due laryngeal oedema, and bradycardia. Prompt administration adrenaline emergent caesarean section allowed the delivery neonate. When inducing labour, quick identification treatment anaphylaxis reactions are necessary prevent maternal neonatal morbidity mortality.