Anaphylaxis to Lumason Contrast agent in Echocardiography after Immune Sensitization: A Case Report and Literature Review

With the continued evolution of echocardiography techniques, novel contrast agents have been introduced to aid in evaluating cardiac structure and function. Lumason is an FDA-approved ultrasound-enhancing agent made Sulfur hexafluoride lipid-type A microspheres. We report a case Lumason-induced immune sensitization subsequent anaphylaxis on re-exposure middle-aged male patient presenting with symptoms concerning for cerebrovascular accident. The was successfully treated steroids antihistamines. Providers, including physicians, technicians, mid-level providers should be aware prepared respond possibility contrast-enhancing used echocardiography.