Analytical evaluation of Radiometer ABL90 FLEX PLUS enzymatic creatinine assay
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چکیده
منابع مشابه
Evaluation of an Enzymatic Method for Determining Serum Creatinine Assay
The enzymatic method for the determination of serum creatinine is accepted as one of the standard method in a clinical laboratory. The enzymatic method for the determination of serum creatinine was optimized for use with Merilyzer AutoQuant-400 auto analyzer and its performance characteristics were practically compared with Jaffe’s Kinetic. Effects of some interfering substances like Serum bili...
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A two-step method for assaying creatinine in serum and urine samples, suitable with automated analyzers, is reported. Reagent 1, for the first step, contains a blanking system [creatine amidinohydrolase (CRTase), urease, glutamate dehydrogenase, NADPH, and 2-oxoglutarate] and a NADPH-regenerating system [Mg(2+)-dependent isocitrate dehydrogenase (ICD), MgCl2, and excess isocitrate]. Reagent 2, ...
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An enzymatic kit method for the determination of plasma creatinine was optimised for use with a centrifugal analyser and its performance characteristics and practicability compared with an end point and a kinetic Jaffé-based method. The enzymatic method exhibited several advantages over Jaffé-based methods--namely, smaller sample size, rapid sample throughput (200 per hour), and improved specif...
متن کاملA multicentric evaluation of IDMS-traceable creatinine enzymatic assays.
Chronic kidney disease definition is based on glomerular filtration rate (GFR) estimations which are derived from creatinine-based equations. The accuracy of GFR estimation is thus largely dependent of those of serum creatinine assays. International recommendations highlight the need for traceable creatinine assays. The French Society of Clinical Biochemistry conducted a study for measuring acc...
متن کاملPseudohypercreatininaemia in two patients caused by monoclonal IgM interference with enzymatic assay of creatinine.
INTRODUCTION Creatinine is released into the blood following non-enzymatic hydrolysis of creatine in skeletal muscle, and excreted into urine depending on glomerular filtration. The serum creatinine concentration is widely used as a marker of glomerular function because it increases in patients with decreased glomerular filtration rate (GFR). Although GFR is costly to measure, an estimated GFR ...
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ژورنال
عنوان ژورنال: Journal of Laboratory and Precision Medicine
سال: 2019
ISSN: 2519-9005
DOI: 10.21037/jlpm.2019.07.01