Analysis of the hexon gene sequence of bovine adenovirus type 4 provides further support for a new adenovirus genus (Atadenovirus).

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Production of Recombinant Adenovirus Containing Human Interlukin-4 Gene

Objective(s) Recombinant adenoviruses are currently used for a variety of purposes, including in vitro gene transfer, in vivo vaccination, and gene therapy. Ability to infect many cell types, high efficiency in gene transfer, entering both dividing and non dividing cells, and growing to high titers make this virus a good choice for using in various experiments. In the present experiment, a reco...

متن کامل

Sequencing and comparative analysis of hexon gene of fowl adenovirus 4 of Indian origin

The sequencing of the recombinant plasmid containing 2916 bp hexon gene insert of fowl adeno virus 4 (FAV4) of Indian origin revealed the complete nucleotide sequence of the FAV4 hexon gene. The sequence analysis revealed an open reading frame of 2814 bp coding for a 937 amino acids long polypeptide with a molecular mass of 106.04 kDa. This sequence was larger than the hexon coding regions of F...

متن کامل

Identification of a Critical and Conformational Neutralizing Epitope in Human Adenovirus Type 4 Hexon

Human adenovirus type 4 (HAdV-4) is an epidemic virus that contributes to serious acute respiratory disease (ARD) in both pediatric and adult patients. However, no licensed drug or vaccine is currently available to the civilian population. The identification of neutralizing epitopes of HAdV-4 should allow the development of a novel antiviral vaccine and a novel gene transfer vector, and an effe...

متن کامل

Neutralizing epitopes mapping of human adenovirus type 14 hexon.

Human adenoviruses 14 (HAdV-14) caused several clusters of acute respiratory disease (ARD) outbreaks in both civilian and military settings. The identification of the neutralizing epitopes of HAdV-14 is important for the surveillance and control of infection. Since the previous studies had indicated that the adenoviruses neutralizing epitopes were likely to be exposed on the surface of the hexo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1998

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-79-6-1453