Analysis of symptoms and clinical signs of laryngopharyngeal reflux depending on pepsia in saliva

In the last fifty years, an epidemic of reflux disease has occurred as a result poor eating habits, stress, and activities food industry. Part this is laryngopharyngeal reflux, characterized by return gastric contents to throat surrounding organs, leading hoarseness, coughing, difficulty in swallowing breathing, ultimately development benign malignant changes larynx. This study aimed examine symptoms signs group before after therapy compare concentration pepsin saliva with above. The prospective longitudinal cohort included 50 subjects, divided into two groups. first consisted 25 subjects reflux. second healthy without Symptoms were collected using RSI RFS questionnaires. Pepsin was measured Peptest therapy. most pronounced are postnasal drip, feeling "a lump throat". median score three months reduced from 20 8. From group, 7 had measurable levels saliva, none control no found have their saliva. Significant improvement observed clinical findings (subglottic edema, posterior commissure hypertrophy, vocal cord dense endolaryngeal secretion) LPR. No association LPR but there significant positive between finding erythema/hyperemia. cases, we start medication. It is, therefore, important emphasize that treatment must always begin change diet, lifestyle, stress regulation. Treatment be individual should include multidisciplinary team nutritionist, psychologist, psychiatrist.