Analysis of spermatogenesis in non-obstructive azoospermic and virtually azoospermic men with known testicular pathology
نویسندگان
چکیده
منابع مشابه
High prevalence of testicular cancer in azoospermic men without spermatogenesis.
BACKGROUND An increased risk of testicular cancer in men with infertility and poor semen quality has been reported. Our aim was to investigate the prevalence of testicular nodules and cancer in azoospermic subjects with different spermatogenetic patterns. METHODS A total of 1443 consecutive infertile men were investigated, out of which 145 (10.0%) were found to be azoospermic. By using clinic...
متن کاملP-195: Analysis of Expression Level of Tex11 Gene in Obstructive and Non-Obstructive Azoospermic Men Referred to Royan Institute
Background: About 15% of couples worldwide suffer from infertility problem that half of these cases are related to male infertility. Spermatogenesis is a cumulative process and thousands of genes are involved in it. Change in one of these genes or their products can cause male infertility. Tex11 is a germ cell specific gene that is located on the X chromosome (Xq13.1 region). This gene was iden...
متن کاملP-198: Analysis of Expression Level of TEX12 Gene in Testis Tissues of Severe Oligozoospermic and Non-Obstructive Azoospermic Men
Background: During the first meiotic prophase, alignment and synapsis of the homologous chromosomes are mediated by the synaptonemal complex. Incorrect assembly of the synaptonemal complex leads to impaired recombination and cell death, which in humans, causes infertility in males. Testis-expressed gene 12 (TEX12) is a germ cell-specific gene that is located on the chromosome 11 (11q22) in huma...
متن کاملTesticular Sperm Retrieval in Azoospermic Men
Peter Pantke , Thorsten Diemer , Marcelo Marconi , Martin Bergmann , Klaus Steger , Hans-Christian Schuppe , Wolfgang Weidner * Department of Urology and Pediatric Urology, University of Giessen, Giessen, Germany b Institute of Veterinary Anatomy, Histology and Embryology, University of Giessen, Giessen, Germany Centre for Dermatology and Andrology, University of Giessen, Giessen, Germany e u r...
متن کاملSerum Metabolomic Profiling Identifies Characterization of Non-Obstructive Azoospermic Men
Male infertility is considered a common health problem, and non-obstructive azoospermia with unclear pathogenesis is one of the most challenging tasks for clinicians. The objective of this study was to investigate the differential serum metabolic pattern in non-obstructive azoospermic men and to determine potential biomarkers related to spermatogenic dysfunction. Serum samples from patients wit...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2009
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(10)60120-4