Analysis of finite dose dermal absorption data: Implications for dermal exposure assessment
نویسندگان
چکیده
منابع مشابه
on dermal exposure assessment
hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. these exposure routes constitute the overall exposure burden on the body. most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked. several studies have already highlighted the importance ...
متن کاملOn dermal exposure assessment.
Hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. These exposure routes constitute the overall exposure burden on the body. Most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked.Several studies have already highlighted the importance o...
متن کاملConceptual model for assessment of dermal exposure.
Dermal exposure, primarily to pesticides, has been measured for almost half a century. Compared with exposure by inhalation, limited progress has been made towards standardisation of methods of measurement and development of biologically relevant exposure measures. It is suggested that the absence of a consistent terminology and a theoretical model has been an important cause of this lack of pr...
متن کاملAssessment of asphalt workers' dermal exposure.
We agree with McClean and his co-workers (McClean et al., 2004) that urinary 1-hydroxypyrene concentration is a useful measure of total absorbed dose of polycyclic aromatic hydrocarbons (PAHs). Many occupational health studies have reported low correlations between inhalation exposures and urinary 1-hydroxypyrene levels, suggesting that other exposure routes (in particular dermal, but also inge...
متن کاملDermal Absorption of Chlorpyrifos
Geer et al. (2004) provided an interesting comparison between passive dosimetry measures and biomonitoring for chlorpyrifos (CP) exposure in pesticide workers. However, they made a questionable assumption of a 3% dermal absorption factor (DAF) for CP, stating: ‘[The] study by Nolan et al. (1984), supports the use of a 3% DAF, the Environmental Protection Agency (EPA) accepted value, whereas Kri...
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ژورنال
عنوان ژورنال: Journal of Exposure Science & Environmental Epidemiology
سال: 2013
ISSN: 1559-0631,1559-064X
DOI: 10.1038/jes.2013.23