Analysis of extemporaneous oral liquid from commercially available drugs in hospital
نویسندگان
چکیده
منابع مشابه
Analysis of extemporaneous oral liquid from commercially available drugs in hospital
The objective of this study was to identify drugs that received dose adjustments (DA) and pharmaceutical alternatives (PA) that avoid DA, and calculate the economic percentage of this replacement. A descriptive, observational and cross-sectional study was performed in a second level hospital. The pharmacy and nursing services was accompanied to identify the drugs that received DA and the compou...
متن کاملExtemporaneous benznidazole oral suspension prepared from commercially available tablets for treatment of Chagas disease in paediatric patients.
OBJECTIVE To develop an extemporaneous 1% benznidazole (BNZ) suspension, with masked taste and adequate stability starting from available commercial tablets. The quality of compounding was evaluated through content uniformity measurement and physical and microbiological stability evaluation, under different storage conditions during 90 days. METHODS Six batches of 1% BNZ suspension were prepa...
متن کاملExtemporaneous Furosemide Suspensions for Pediatrics Use Prepared from Commercially Available Tablets
Objective: Three furosemide aqueous suspensions for paediatric oral usage (2 mg/ml) were investigated to determinate its physicochemical stability under different storage conditions. Method: Formulations using sugar syrup and sugar-free vehicles were stored at 4 and 25 o C and the furosemide content was determined by spectrophotometer. Each sample was analyzed in triplicate at different time po...
متن کاملExtemporaneous clobazam suspensions for paediatric use prepared from commercially available tablets and pure drug.
OBJECTIVE Two clobazam aqueous suspensions for paediatric oral usage (5 mg/ml) were investigated to determinate its physicochemical stability under different storage conditions. METHOD Formulations were stored at 4 and 25 °C and the clobazam content was determined by High Performance Liquid Chromatography. Each sample was analyzed by triplicate at different time points (0, 7, 14, 28 and 56 da...
متن کاملStability of extemporaneous enalapril maleate suspensions for pediatric use prepared from commercially available tablets.
In this paper, the stability of enalapril maleate in oral formulations prepared from commercially available tablets was investigated. Extemporaneously compounded, 0.1 mg/mL and 1.0 mg/mL, oral suspensions of enalapril maleate in sugar-containing and sugar-free vehicles were stored in the absence of light at 4 degrees and 25 degrees C for 30 days. Enalapril maleate stability was quantified after...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 1984-8250
DOI: 10.1590/s1984-82502016000300017