Analysis of diabetic ketoacidosis

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Management of Diabetic Ketoacidosis in Children

Diabetic ketoacidosis (DKA) is one of the leading causes of mortality in diabetic children. This study aimed to determine the frequency of mortality and complications of DKA during treatment in order to make the necessary modifications with regard to the common treatment problems. This was a cross sectional study, where patients were selected by examining the records of 112 children under the ...

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Diabetic ketoacidosis.

A diagnosis of diabetic ketoacidosis requires the patient's plasma glucose concentration to be above 250 mg per dL (although it usually is much higher), the pH level to be less than 7.30, and the bicarbonate level to be 18 mEq per L or less. Beta-hydroxybutyrate is a better measurement of the degree of ketosis than serum ketones. Intravenous insulin and fluid replacement are the mainstays of th...

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Diabetic Ketoacidosis

A chronic autoimmune destruction of the pancreatic beta cells results in decreasing endoge‐ nous insulin secretion and the clinical manifestation of type 1 diabetes mellitus (T1DM). The clinical onset of the disease is often acute in children and adolescents and diabetic ketoaci‐ dosis (DKA) is present in 20-74% of the patients [1-7]. DKA is a serious condition that re‐ quiring immediate interv...

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Management of diabetic ketoacidosis

Although the mortality of diabetic ketoacidosis (DKA) has decreased substantially in the developed world, high mortality rates still prevail in South Africa, thus making this an important condition to recognise early and manage well. This review discusses the treatment of DKA, with emphasis on the controversial aspect of initial fluid replacement therapy. Current guidelines recommend the use of...

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Spironolactone and diabetic ketoacidosis.

Introduction Spironolactone is a specific competitive antagonist of aldosterone, the most potent endogenous mineralocorticoid, which modifies renal electrolyte handling and is therefore commonly used as a diuretic in conditions associated with secondary hyperaldosteronism. In renal insufficiency, aldosterone antagonists may induce significant hyperkalaemia even if administered concurrently with...

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ژورنال

عنوان ژورنال: Avicenna Journal of Medicine

سال: 2016

ISSN: 2231-0770

DOI: 10.4103/2231-0770.179548