Anaerobic C-ring cleavage of genistein and daidzein byEubacterium ramulus

Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine.

The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known for some time, the corresponding formation of 5-hydroxy-equol from genistein has not been reported previously. We isolated a strictly a...

Daidzein and genistein contents of vegetables.

Food samples (n 114) were prepared from vegetables commonly eaten in Europe. The glycosidic forms of the phyto-oestrogens daidzein and genistein were extracted from the dried foods into aqueous methanol. The isoflavones were quantified by GC-MS after hydrolytic removal of any conjugated carbohydrate. Completeness of extraction and any procedural losses of the isoflavones were accounted for usin...

Anaerobic Bacterium Newly Isolated from Conversion of Daidzein and Genistein by an

The Combined Effects Of Genistein And Daidzein On Adipocyte Differentiation

iii ACKNOWLEDGEMENTS I would like to express my gratitude to my advisor, Dr. Young-Cheul Kim, and the opportunity he provided me to complete this project. He has generously offered his hand and his heart in support and guidance for me as a developing young researcher. I would like to thank committee member, Dr. Richard Wood, for his encouraging words, thoughtful comments and suggestions, inspir...

Daidzein and genistein concentrations in human milk after soy consumption.

Soy isoflavones were quantified from human milk by a fast, precise, and selective HPLC method after enzymatic hydrolysis of conjugated isoflavones and extraction with ethyl acetate. Isoflavone aglycones and their mammalian metabolites equol and O-desmethylangolensin were separated selectively and identified by absorbance patterns, fluorometric and electrochemical detection, gas chromatography-m...