An Overview About Acne Vulgaris

Background: Acne vulgaris (acne) is a long-term inflammatory skin disease. Typical features of acne that often appears in adolescents on the forehead include visible, clinically recognized blackheads or whiteheads (comedones) develop into red papules pustules and possible scarring. primarily affects with relatively high number sebaceous glands including face, neck, chest, upper back. postinflammatory hyperpigmentation have strong negative impact mental health, mood disorde,r, depression, suicidal thoughts. Also may cause low self-esteem, decrease social interactions quality-of-life scores adolescents. increased secretion sebum by skin, microcomedones (a structure invisible to naked eye), comedones, papules, nodules, pustules, results It result psychological problems. lesions are classified non inflammatory. Non consist open closed comedones. Open comedones clearly obvious can be found face centrally. Closed inspection good light room, slightly hypopigmented ,tiny, usually less than 1mm size, no visible opening . Comedones superficial remain progress get inflammed become deep. Inflammatory ( red, inflammed, raised size 5 mm), scattered pus-filled papules) nodules lesions, mm larger size). these affect deep structures so their inflammation lead formation scars. chronic disease pilosebaceous unit occurs as following four factors: production (due activity androgens IGF-1), excessive deposition keratin follicles leading comedo formation, colonization follicle P. acnes bacteria, local release pro-inflammatory chemicals through certain mechanisms. Limited evidence supports extraction, but it an option for do not improve standard treatment. Another procedure immediate relief injection corticosteroid inflamed comedo. Electrocautery electrofulguration effective alternative treatments non-inflammatory common vulgaris, which complex illness linked follicle. Since occur both early stages late disease, plays critical role development non-inflammatory. There different updated modalities