An Organotin Mixture Found in Polyvinyl Chloride (PVC) Pipe is not Immunotoxic to Adult Sprague-Dawley Rats
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Keishibukuryogan is not carcinogenic in Sprague-Dawley rats
Keishibukuryogan is a traditional Japanese medicine widely administered to patients with menopausal symptoms. Because humans use it on a long-term basis, we believed that a carcinogenicity study was warranted. We orally administered keishibukuryogan (TJ-25) extract powder to 6-week-old Sprague-Dawley rats [Crl:CD(SD)], which were divided into four dosage groups-0 (water for injection), 100, 500...
متن کامل[Determination of organotin compounds in polyvinyl chloride toys].
Organotin compounds in polyvinyl chloride toys were determined by GC/MS after ethyl derivatization with sodium tetraethylborate. The samples were 12 balls, 12 soft toys, 10 food toys and 13 face masks for children. Monooctyltin, dioctyltin and trioctyltin compounds were found in all face masks at the levels of 74.8-917 micrograms/g. 474-3,960 micrograms/g and 1.0-213 micrograms/g, respectively....
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An existing deteriorated or hydraulically undersized pipe can be replaced with a new pipe by static pipe bursting. Cavity expansion during pipe bursting induces ground movements, which may potentially damage nearby buried utilities if they are in close proximity to the pipe bursting operation. A large-scale pipe bursting experiment was performed in an 8 m long, 8 m wide, and 3 m deep test pit f...
متن کاملEffects of Sodium Selenite in Cadmium Chloride Induced Hepatoxicity in Male Sprague-Dawley Rats
The present study aimed to assess the protective role of selenium against cadmium induced hepatotoxicity. The rats were given subcutaneous doses of 1mg/Kg body weight of either normal saline or cadmium chloride or sodium selenite or cadmium chloride plus sodium selenite on alternate days for four weeks. The results showed that cadmium treatment increased hepatic levels of lipid peroxidation, DN...
متن کاملComparative toxicokinetics of manganese chloride and methylcyclopentadienyl manganese tricarbonyl (MMT) in Sprague-Dawley rats.
The toxicokinetics of manganese (Mn) was investigated in male and female rats either following a single intravenous (iv) or oral dose of MnCl2 (6.0 mg Mn/kg), or following a single oral dose of methylcyclopentadienyl manganese tricarbonyl (MMT) (20 mg MMT/kg or 5.6 mg Mn/kg). The plasma concentrations of manganese were quantified by atomic absorption spectrophotometry (AAS). Upon iv administrat...
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ژورنال
عنوان ژورنال: Journal of Toxicology and Environmental Health, Part A
سال: 2008
ISSN: 1528-7394,1087-2620
DOI: 10.1080/15287390701613025