An Obese Pregnant Woman with Type 2 Diabetes Whose One-Day Insulin Requirements Were 1,000 IU

serum adiponectin levels are inversely correlated with insulin resistance in obese men with type 2 diabetes

Severe HDL-c reduction during rosiglitazone therapy in an obese woman with type 2 diabetes.

Treatment with rosiglitazone has been associated with severe paradoxical HDL-c reductions. To our knowledge, there are very few reports of this reaction occurring when patients are treated without the combination of a fibrate. A case of severe HDL-c lowering in a patient treated with rosiglitazone without a fibrate is presented. The patient has been treated at a private practice clinic in south...

Effects of Combined Training on Progranulin, Glycosylated Hemoglobin, and Insulin Resistance in Overweight and Obese Women with Type 2 Diabetes

Introduction: Progranulin (PGRN) has been recently introduced as a new indicator of chronic inflammatory response in type 2 diabetes. The present study aimed to investigate the effect of combined training on serum levels of progranulin, glycosylated hemoglobin (HbA1c), and insulin resistance in overweight and obese women with type 2 diabetes. Materials and Methods: A total of 36 women were divi...

Insulin Autoantibody-Related Hypoglycemic Coma in a Pregnant Woman with Type 1 Diabetes Mellitus

1Division of Endocrinology and Metabolism, Department of Internal Medicine 2Department of Nursing, National Taiwan University Hospital, Taiwan 3Department of Dietetics, National Taiwan University Hospital, Taiwan 4Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taiwan 5Department of Obstetrics and Gynecology, Taiwan 6Department of Internal Medicine, College of Medi...

Pharmacokinetics of insulin aspart in pregnant women with type 1 diabetes: every day is different.

Rapid-acting insulin analogs are increasingly used during type 1 diabetic pregnancy. They may assist women to safely optimize glucose control (1,2), but little is known about their pharmacokinetics and reproducibility in pregnancy. Using a unique data set of 1,300 plasma insulin samples collected under strictly observed experimental conditions, we explored the relationship between aspart pharma...