An Improved and Reliable Method for the Induction of Colitis in Rats Using 2,4,6-Trinitrobenzene Sulfonic Acid
نویسندگان
چکیده
منابع مشابه
An improved and reliable method for the induction of colitis in rats using 2,4,6-trinitrobenzene sulfonic acid.
We performed this study to develop a reliable method for inducing colitis in rats using 2,4,6-trinitrobenzene sulfonic acid (TNBS) to reduce the variation in ulcer size. A pair of ring forceps was used to clamp the colon and 0.1 M TNBS in ethanol was injected into the luminal side of the clamped portion. This method resulted in a small coefficient of variation of the ulcer index. A significant ...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2005
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.scj04008x