An IMiD-induced SALL4 degron system for selective degradation of target proteins
نویسندگان
چکیده
منابع مشابه
A photosensitive degron enables acute light-induced protein degradation in the nervous system
Acutely inducing degradation enables studying the function of essential proteins. Available techniques target proteins post-translationally, via ubiquitin or by fusing destabilizing domains (degrons), and in some cases degradation is controllable by small molecules. Yet, they are comparably slow, possibly inducing compensatory changes, and do not allow localized protein depletion. The photosens...
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ژورنال
عنوان ژورنال: Communications Biology
سال: 2020
ISSN: 2399-3642
DOI: 10.1038/s42003-020-01240-5