An Evaluation of Hybridoma based Anti-tick Vaccine against H. Dromedarii Tick Infesting Camels
نویسندگان
چکیده
Background: Ticks and tick-borne diseases (TBDs) are considered to be the most serious health problems for animals humans. This issue prompts veterinarians researchers adopt better preventive control strategies. Therefore, this study aims develop hybridoma vaccine against Hylomma dromedarii infesting Camelus dromedaries. Methods: Myeloma cell culture was administered immunized mouse in order produce hybridomas cells. These cells were then emulsified with Montanide ISA-51 adjuvant. Two doses of prepared anti-tick intradermally camels an interval five weeks. The humoral response experimental measured by indirect enzyme-linked immunosorbent assay (ELISA). Result: There a significant (p less than 0.05) decrease immune responses tick counts molting capacity. Overall, 85% efficacy developed recorded. It is concluded that based effective controlling H. infestation camels.
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ژورنال
عنوان ژورنال: Indian Journal of Animal Research
سال: 2022
ISSN: ['0367-6722', '0976-0555']
DOI: https://doi.org/10.18805/ijar.bf-1540