An etiological role for aeroallergens and eosinophils in experimental esophagitis
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چکیده
منابع مشابه
An etiological role for aeroallergens and eosinophils in experimental esophagitis.
Eosinophil infiltration into the esophagus is observed in diverse diseases including gastroesophageal reflux and allergic gastroenteritis, but the processes involved are largely unknown. We now report an original model of experimental esophagitis induced by exposure of mice to respiratory allergen. Allergen-challenged mice develop marked levels of esophageal eosinophils, free eosinophil granule...
متن کاملAn Etiological Role for Aeroallergens and Eosinophils in Experimental Esophagitis
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Pathogenic role of mast cells in experimental eosinophilic esophagitis.
Eosinophilic esophagitis (EoE) is a chronic allergic disease characterized by esophageal intraepithelial eosinophils, extracellular eosinophil granule deposition, induced mast cell accumulation, and epithelial cell hyperplasia. However, the processes involved in the development of a number of these characteristics are largely unknown. Herein, we tested the hypothesis whether induced mast cell a...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2001
ISSN: 0021-9738
DOI: 10.1172/jci10224