An Engineered Nanosugar Enables Rapid and Sustained Glucose‐Responsive Insulin Delivery in Diabetic Mice (Adv. Mater. 21/2023)
نویسندگان
چکیده
Insulin Delivery In article number 2210392, Christoph E. Hagemeyer, Francesca Cavalieri, and co-workers report how biodegradable charge-switchable phytoglycogen nanoparticles with glucose-sensitive phenylboronic acid groups amine moieties can be engineered to form nanocomplexes insulin for its rapid efficient glucose-responsive delivery. Subcutaneous injection of in two distinct diabetic mouse models helps maintain normal glucose levels up 13 h.
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ژورنال
عنوان ژورنال: Advanced Materials
سال: 2023
ISSN: ['1521-4095', '0935-9648']
DOI: https://doi.org/10.1002/adma.202370146