An Empirical Extremum Principle for the Hill Coefficient in Ligand-Protein Interactions Showing Negative Cooperativity

An extremum principle of evaporation

[1] It is proposed, on the basis of an argument of thermodynamic equilibrium, that land-atmosphere interactive processes lead to thermal and hydrologic states of the land surface that maximize evaporation in a given meteorological environment. The extremum principle leads to general equations linking surface energy fluxes to surface temperature and soil moisture. The hypothesis of maximum evapo...

An Extremum Principle for a Neutron Diffraction Experiment

An extremum principle was postulated by Horne, Finkelstein, Shull, Zeilinger, and Bernstein in order to derive the physically allowable parameters for sinusoidal standing waves governing a neutron in a crystal which is immersed in a strong external magnetic field: `̀ the expectation value of the total potential á V ñ is an extremum .’’ We show that this extremum principle can be obtained from th...

the search for the self in becketts theatre: waiting for godot and endgame

this thesis is based upon the works of samuel beckett. one of the greatest writers of contemporary literature. here, i have tried to focus on one of the main themes in becketts works: the search for the real "me" or the real self, which is not only a problem to be solved for beckett man but also for each of us. i have tried to show becketts techniques in approaching this unattainable goal, base...

PLIO: an ontology for formal description of protein-ligand interactions

MOTIVATION Biomedical ontologies have proved to be valuable tools for data analysis and data interoperability. Protein-ligand interactions are key players in drug discovery and development; however, existing public ontologies that describe the knowledge space of biomolecular interactions do not cover all aspects relevant to pharmaceutical modelling and simulation. RESULTS The protein--ligand ...

Protein Ligand Interactions