An association study between catechol-O-methyl transferase gene polymorphism and methamphetamine psychotic disorder
نویسندگان
چکیده
منابع مشابه
association of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia
background : a single nucleotide variation within atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...
متن کاملAssociation of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia
BACKGROUND A single nucleotide variation within catechol-o-methyl transferase (COMT) gene may alter the COMT enzyme activity level. Polymorphism of Val158Met in the COMT gene has been related to malignancy. In this regard, a study was carried out to find a possible association between the COMT gene polymorphism in patients with sporadic prostate cancer (PCa) and benign prostatic hyperplasia (BP...
متن کاملAssociation between Catechol-O-Methyltransferase Gene Variant and Bipolar Disorder
Emotional dysregulation is a core characteristic of many psychiatric diseases. Bipolar disorder is a brain disorder that causes unusual shifts in mood, energy level, activity level and ability to carry day to day work. CatecholO-methyltransferase (COMT) is involved in the metabolism of dopamine and epinephrine. To a large extent it is responsible in maintaining human cognitive functioning. Poly...
متن کاملCatechol-O-methyl transferase and schizophrenia.
Catechol-O-methyl transferase (COMT) is an enzyme involved in the degradation of dopamine. The most commonly examined polymorphism within the COMT gene is Val108/158Met polymorphism, which results in three to fourfold difference in COMT enzyme activity. It is particularely important in prefrontal cortex, since COMT activity is the most important regulator of the prefrontal dopamine function. Gi...
متن کاملAssociation Study of FYN Gene Polymorphism and Methamphetamine Use Disorder
Fyn kinase belongs to the Src family of tyrosine kinases and phosphorylates NMDA receptor subunits. The Fyn kinase gene, FYN, has been considered to be involved in the pathophysiologies of neuropsychiatric diseases. We examined three polymorphisms, rs706895, rs3730353, and rs6916861, of the FYN gene in 250 patients with methamphetamine use disorder and 275 controls. There were no significant di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Psychiatric Genetics
سال: 2006
ISSN: 0955-8829
DOI: 10.1097/01.ypg.0000218613.35139.cd