An aptameric graphene nanosensor for label-free detection of small-molecule biomarkers
نویسندگان
چکیده
منابع مشابه
An aptameric graphene nanosensor for label-free detection of small-molecule biomarkers.
This paper presents an aptameric graphene nanosensor for detection of small-molecule biomarkers. To address difficulties in direct detection of small molecules associated with their low molecular weight and electrical charge, we incorporate an aptamer-based competitive affinity assay in a graphene field effect transistor (FET), and demonstrate the utility of the nanosensor with dehydroepiandros...
متن کاملDesigning a Label Free Aptasensor for Detection of Methamphetamine
A label-free electrochemical nucleic acid aptasensor for the detection of methamphetamine (MA) by the immobilization of thiolated self-assembled DNA sequences on a gold nanoparticles-chitosan modified electrode is constructed. When MA was complexed specifically to the aptamer, the configuration of the nucleic acid aptamer switched to a locked structure and the interface of the biosensor changed...
متن کاملA label-free optical technique for detecting small molecule interactions.
A novel approach for the label-free detection of molecular interactions is presented in which a colorimetric resonant grating is used as a surface binding platform. The grating, when illuminated with white light, is designed to reflect only a single wavelength. When molecules are attached to the surface, the reflected wavelength (color) is shifted due to the change of the optical path of light ...
متن کاملGraphene based nanosensor for aqueous phase detection of nitroaromatics
A graphene-based nanosensor was fabricated to selectively detect nitrotriazolone (NTO) molecules with a molecularly imprinted film via simple electrical measurements. Molecularly imprinted polymer comprising chitosan was used as sensitive layer. Gold electrodes for electrical measurements were lithographically fabricated on Si/SiO2 substrate, followed by monolayer graphene transfer and polymeri...
متن کاملdesigning a label free aptasensor for detection of methamphetamine
a label-free electrochemical nucleic acid aptasensor for the detection of methamphetamine (ma) by the immobilization of thiolated self-assembled dna sequences on a gold nanoparticles-chitosan modified electrode is constructed. when ma was complexed specifically to the aptamer, the configuration of the nucleic acid aptamer switched to a locked structure and the interface of the biosensor changed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biosensors and Bioelectronics
سال: 2015
ISSN: 0956-5663
DOI: 10.1016/j.bios.2015.04.025