An Ancestral miR-1304 Allele Present in Neanderthals Regulates Genes Involved in Enamel Formation and Could Explain Dental Differences with Modern Humans
نویسندگان
چکیده
منابع مشابه
Dental evidence for ontogenetic differences between modern humans and Neanderthals.
Humans have an unusual life history, with an early weaning age, long childhood, late first reproduction, short interbirth intervals, and long lifespan. In contrast, great apes wean later, reproduce earlier, and have longer intervals between births. Despite 80 y of speculation, the origins of these developmental patterns in Homo sapiens remain unknown. Because they record daily growth during for...
متن کاملFacial ontogeny in Neanderthals and modern humans.
One hundred and fifty years after the discovery of Neanderthals, it is held that this morphologically and genetically distinct human species does not differ from modern Homo sapiens in its craniofacial ontogenetic trajectory after the early post-natal period. This is striking given the evident morphological differences between these species, since it implies that all of the major differences ar...
متن کاملWhen Did Neanderthals and Modern Humans Diverge?
The availability of sequences from the mtDNA hypervariable region I and II of a specimen of the Neanderthal,1,2 Homo neanderthalensis, permits estimation of the time of divergence of Neanderthals and modern humans. Based on substitution rates derived from comparison of human and chimpanzee, Krings et al. provided an estimate of 550–690 KY1 and 317–741 KY2 before present for the split between th...
متن کاملBrain development is similar in Neanderthals and modern humans
While the braincase of adult Neanderthals had a similar volume to that of modern humans from the same period, differences in endocranial shape suggest that brain morphology differed between modern humans and Neanderthals. When and how these differences arose during evolution and development is a topic of ongoing research, with potential implications for species-specific differences in brain and...
متن کاملNew insights into differences in brain organization between Neanderthals and anatomically modern humans.
Previous research has identified morphological differences between the brains of Neanderthals and anatomically modern humans (AMHs). However, studies using endocasts or the cranium itself are limited to investigating external surface features and the overall size and shape of the brain. A complementary approach uses comparative primate data to estimate the size of internal brain areas. Previous...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2012
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/mss023