An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A
نویسندگان
چکیده
منابع مشابه
The N-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A.
Hepatitis C virus proteins are produced by proteolytic processing of the viral precursor polyprotein that is encoded in the largest open reading frame of the viral genome. Processing of the nonstructural viral polyprotein requires the viral serine-type proteinase present in nonstructural protein 3 (NS3). The cleavage of the junction between NS4B and NS5A is mediated by NS3 only when NS4A is pre...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1995
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.69.3.1769-1777.1995