An acyclic 5-nitroindazole nucleoside analogue as ambiguous nucleoside
نویسندگان
چکیده
منابع مشابه
An acyclic 5-nitroindazole nucleoside analogue as ambiguous nucleoside.
Acyclic nucleoside analogues with carboxamido- or nitro-substituted heterocyclic bases have been evaluated for their possible use as universal bases in oligodeoxynucleotides. The acyclic moiety endows the constructs with enough flexibility to allow good base stacking. The 5-nitroindazole analogue afforded the most stable duplexes among the acyclic derivatives with the least spread in Tm versus ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1995
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/23.21.4363