Amyloid β Peptide Formation in Cell-free Preparations
نویسندگان
چکیده
منابع مشابه
Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein
Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary pathologic species in Alzheimer's and Parkinson's diseases. However, the molecular mechanisms underlying the assembly of these toxic oligomers in the plasma membrane of brain cells remain unclear. Here we have analyzed and compared the pore-forming capability of a large panel of amyloid proteins including wild...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1996
ISSN: 0021-9258
DOI: 10.1074/jbc.271.40.24670