Amnesic Syndrome in a Mammillothalamic Tract Infarction

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Amnesic Syndrome in a Mammillothalamic Tract Infarction

It is controversial whether isolated lesions of mammillothalamic tract (MTT) produce significant amnesia. Since the MTT is small and adjacent to several important structures for memory, amnesia associated with isolated MTT infarction has been rarely reported. We report a patient who developed amnesia following an infarction of the left MTT that spared adjacent memory-related structures includin...

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Acute Korsakoff syndrome following mammillothalamic tract infarction.

There are limited case reports of structural lesions causing Korsakoff syndrome. This report describes acute Korsakoff syndrome following localized, bilateral infarction of the mammillothalamic tracts (MTTs). Axial T2-weighted imaging revealed the lesions at the lateral wall level of the third ventricle and diffusion-weighted imaging confirmed that the left lesion was new and the right old. Kor...

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Injury of the Mammillothalamic Tract in Patients with Thalamic Hemorrhage

OBJECTIVE Injury of the mammillothalamic tract (MTT) has been suggested as one of the plausible pathogenic mechanisms of memory impairment in patients with thalamic hemorrhage; however, it has not been clearly demonstrated so far. We attempted to investigate whether injury of the MTT documented by diffusion tensor tractography following thalamic hemorrhage correlates with cognitive impairment. ...

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Mammillothalamic tract lesions disrupt dead reckoning in the rat.

Debate surrounds the role of the limbic system structures' contribution to spatial orientation. The results from previous studies have supported a role for the mammillary bodies and their projections to the anterior thalamus in rapid encoding of relationships among environmental cues; however, this work is based on behavioral tasks in which environmental and self-movement cues could not be diss...

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Injury of the mammillothalamic tract in patients with subarachnoid haemorrhage: a retrospective diffusion tensor imaging study

OBJECTIVE Few studies have reported on injury of the mammillothalamic tract (MTT) in patients with stroke. However, no study in patients with subarachnoid haemorrhage (SAH) has been reported. Using diffusion tensor tractography, we attempted to investigate injury of the MTT in patients with SAH. METHODS We recruited 16 patients with SAH and 15 control participants. DTI was obtained at 5.7±1.5...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 2007

ISSN: 1011-8934

DOI: 10.3346/jkms.2007.22.6.1094