Amino Acid Polymorphisms of PrP Gene in Mongolian Sheep.
نویسندگان
چکیده
منابع مشابه
Prion protein gene (PrP) polymorphisms in healthy sheep in Turkey.
Scrapie, a transmissible spongiform encephalopathy (TSE) or prion disease, is a fatal, neurodegenerative disease in sheep and goats. This disease has been known in Europe for more than 250 years. Susceptibility to scrapie is associated with polymorphisms in the sheep prion protein gene (PrP) gene. In sheep, polymorphism in the PrP gene has been identified at a number of codons, and polymorphism...
متن کاملSheep genotyping for PrP gene polymorphisms in rare Greek breeds
L. V. Ekateriniadou, PhD, National Agricultural Research Foundation Veterinary Research Institute, 570 08 Ionia, Thessaloniki, Greece C. H. Panagiotidis, PhD, A. Terzis, BA, T. Sklaviadis, PhD Prion Disease Research Group, School of Pharmacy, Aristotle University of Thessaloniki 54 124 Thessaloniki, Greece A. Triantafyllidis, PhD, P. Deligiannidis, MS, C. Triantaphyllidis, PhD, School of Biolog...
متن کاملPrion protein (PrP) gene polymorphisms and breeding for resistance to scrapie in Polish Merino sheep
Genetic susceptibility or resistance of sheep to scrapie is associated with polymorphisms particularly in the three codons 136, 154 and 171 of the ovine prion protein (PrP) gene. The aim of the study was to reveal the PrP haplotype and genotype distribution in the Polish Merino breed and to make a forecast of the application of a scrapie resistance breeding programme for this breed. PCR-RFLP an...
متن کاملPolymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP
Polymorphisms in ovine PrP at amino acid residues 141 and 154 are associated with susceptibility to ovine prion disease: Leu141Arg154 with classical scrapie and Phe141Arg154 and Leu141His154 with atypical scrapie. Classical scrapie is naturally transmissible between sheep, whereas this may not be the case with atypical scrapie. Critical amino acid residues will determine the range or stability ...
متن کاملAmino acid requirements and amino acid supply in the sheep.
The special features of nitrogen metabolism in ruminants, which stem from the extensive breakdown and synthesis of dietary protein in the rumen (see Hungate, 1966), imply the absence of a specific dietary requirement for essential amino acids. Nevertheless, there is considerable theoretical and practical interest in defining the amino acid requirements of ruminant tissues in animals of known nu...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2003
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.65.75