Amination of Polymeric Braid Structures to Improve Tendon Healing: An Experimental Comparison
نویسندگان
چکیده
Several polymers are researched for tendon repair as polyethylene terephthalate (PET) and polylactic acid (PLA). These biocompatible useful in scaffolding though with minimal success due to long-term failure. There is a need improve such scaffolds' design physical–chemical nature. This work concerns surface functionalization of polymeric braids (PET PLA) that fulfill the high mechanical demands tissues tendons. The aims incorporate amine groups braids' surface, cell adhesion, consequently, poor healing rate these biointegration braids. Two approaches compared: direct application NH3 plasma grafting EDA after O2 activation. X-ray photoelectron spectroscopy (XPS) shows effectively introduced onto samples' surfaces. Besides, parameters chosen do not compromise topography tensile behavior Resazurin assay scanning electron microscopy show treatment improves cell–biomaterial interaction improved adhesion proliferation observed. Both safe biomedical applications. approach more environmentally friendly, faster, easier scale-up, showing potential final hybrid medical device.
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ژورنال
عنوان ژورنال: Macromolecular Materials and Engineering
سال: 2022
ISSN: ['1439-2054', '1438-7492']
DOI: https://doi.org/10.1002/mame.202200426