Amiloride hydrochloride in hypertensive patients.
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منابع مشابه
Amiloride hydrochloride in hypertensive patients.
In man amiloride hydrochloride (MK-870) has been shown to be an orally effective diuretic which causes a positive potassium balance. It also enhances the saluretic effects of hydrochlorothiazide and ethacrynic acid and in addition prevents the negative potassium balance caused by these diuretics (Wilson et al., 1966; Gombos et al., 1966). Gombos et al. also studied its effects in 10 hypertensiv...
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Pathophysiological features of both primary aldosteronism and pseudohyperaldosteronism are hyperactive amiloride-sensitive epithelial Na(+) channels (ENaC) and refractory hypertension. Peripheral blood lymphocytes express ENaC, which functions and is regulated similarly to ENaC expressed by renal principal cells. Thus it was hypothesized that individuals with either of these hypertensive etiolo...
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A new reverse phase high performance liquid chromatography method for the simultaneous estimation of frusemide and amiloride hydrochloride in tablet formulation is developed. The determination was carried out on a HIQ SIL, C18 (250×4.6 mm, 5 µm) column using a mobile phase of 50 mM phosphate buffer solution:acetonitrile (50:50 v/v, pH 3.0). The flow rate was 1.0 ml/min with detection at 283 nm....
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ژورنال
عنوان ژورنال: BMJ
سال: 1968
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5589.422