Amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus.
نویسندگان
چکیده
منابع مشابه
Cell-mediated amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus.
We studied a patient with a rare complication of amegakaryocytic thrombocytopenia (AMT) associated with systemic lupus erythematosus (SLE). To investigate the underlying pathogenesis of AMT, the effects of peripheral blood T cells and serum on human megakaryocyte progenitor cells were studied using in vitro coculture techniques. Mononuclear bone marrow cells (2 X 10(5) from normal donors produc...
متن کاملSuccessful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).
Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease mediated by a deregulated immune system and aberrant production of proinflammatory cytokines leading to multiorgan and tissue damage. Thrombocytopenia is a common complication in patients with SLE, with a prevalence that ranges from 7–30%.1-5 The 2 main mechanisms of thrombocytopenia in SLE are increased platelet de...
متن کاملThrombocytopenia in Systemic Lupus Erythematosus
The aim of the study was to examine the clinical characteristics and prognosis according to severity of thrombocytopenia and response to treatment for thrombocytopenia in patients with systemic lupus erythematosus (SLE). We retrospectively evaluated 230 SLE patients with thrombocytopenia, and reviewed their clinical data and laboratory findings. Thrombocytopenia was defined as platelet counts u...
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Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملSystemic lupus erythematosus, repeated abortions, and thrombocytopenia.
A case is described of severe thrombocytopenia in a pregnant patient with mild SLE. Three previous pregnancies had ended in abortion. Attempts to reverse the thrombocytopenia with steroids, plasmapheresis, and splenectomy failed, the platelet count returning to normal immediately after the death of the fetus at 20 weeks gestation.
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2000
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.89.1430