Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure
نویسندگان
چکیده
منابع مشابه
Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure
INTRODUCTION The objectives were to characterize alveolar fluid clearance (AFC) in pigs with normal lungs and to analyze the effect of immediate application of positive end-expiratory pressure (PEEP). METHODS Animals (n = 25) were mechanically ventilated and divided into four groups: small edema (SE) group, producing pulmonary edema (PE) by intratracheal instillation of 4 ml/kg of saline solu...
متن کاملPositive end-expiratory pressure.
PURPOSE OF REVIEW In the last 2 years, several reports have dealt with recruitment/positive end-expiratory pressure (PEEP) selection. Most of them confirm previous results and few add new information. RECENT FINDINGS It has been definitely confirmed that opening pressures are different throughout the acute respiratory distress syndrome lung parenchyma, ranging from 5-10 up to 30-40 cmH2O. The...
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Background: Pulmonary complications following valvular heart surgery are common and contribute to increased duration of hospital stay, rate of morbidity, and mortality. The purpose of the present study was to investigate the response of maximum inspiratory pressure and functional capacity to Positive End-Expiratory Pressure device in patients who underwent valvular hea...
متن کاملEffects of duty cycle and positive end-expiratory pressure on mucus clearance during mechanical ventilation*.
OBJECTIVES During mechanical ventilation, air flows may play a role in mucus transport via two-phase gas liquid flow. The aim of this study was to evaluate effects of duty cycles and positive end-expiratory pressure on mucus clearance in pigs using mechanical ventilation, and to assess their safety. DESIGN Prospective randomized animal study. SETTING Animal research facility, University of ...
متن کاملEffect of positive end-expiratory pressure and tidal volume on lung injury induced by alveolar instability
INTRODUCTION One potential mechanism of ventilator-induced lung injury (VILI) is due to shear stresses associated with alveolar instability (recruitment/derecruitment). It has been postulated that the optimal combination of tidal volume (Vt) and positive end-expiratory pressure (PEEP) stabilizes alveoli, thus diminishing recruitment/derecruitment and reducing VILI. In this study we directly vis...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2010
ISSN: 1364-8535
DOI: 10.1186/cc8914