Altered Tumor Necrosis Factor- (TNF- ) Processing in Adipocytes and Increased Expression of Transmembrane TNF- in Obesity
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چکیده
منابع مشابه
Membrane tumor necrosis factor (TNF) induces p100 processing via TNF receptor-2 (TNFR2).
Tumor necrosis factor (TNF) elicits its biological activities by stimulation of two receptors, TNFR1 and TNFR2, both belonging to the TNF receptor superfamily. Whereas TNFR1-mediated signal transduction has been intensively studied and is understood in detail, especially with respect to activation of the classical NFkappaB pathway, cell death induction, and MAP kinase signaling, TNFR2-associate...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2002
ISSN: 0012-1797,1939-327X
DOI: 10.2337/diabetes.51.6.1876