Altered lipid content inhibits autophagic vesicular fusion
نویسندگان
چکیده
منابع مشابه
Non-vesicular and vesicular lipid trafficking involving plastids.
In plants, newly synthesized fatty acids are either directly incorporated into glycerolipids in the plastid or exported and assembled into lipids at the endoplasmic reticulum (ER). ER-derived glycerolipids serve as building blocks for extraplastidic membranes. Alternatively, they can return to the plastid where their diacylglycerol backbone is incorporated into the glycerolipids of the photosyn...
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A general method for synthesizing 5(')- and 3(')-coupled DNA-lipid conjugates has been developed and employed in DNA-mediated vesicle fusion. Vesicles presenting complementary DNA fuse, resulting in both outer and inner leaflet mixing as well as content mixing. Fusion is maximized using 5(')- and 3(')-coupled DNA on opposite vesicle partners, rather than only 5(')-coupled DNA, showing the impor...
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Exocytic post-fusion events play an important role determining the composition and quantity of cellular secretion. In particular, Ca(2+)-dependent regulation of fusion pore dilation/closure is a key regulator for fine-tuning vesicle content secretion. This requires a tight temporal and spatial integration of vesicle fusion with the PM, Ca(2+) signals and translation of the Ca(2+) signal into fu...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.09-144519