Alteration of Pulmonary Venous Flow Doppler Post Transcatheter Closure of Atrial Septal Defect

Background: Atrial septal defect is a common congenital heart anomaly results in hemodynamically significant right ventriclular volume overload and an increase the pulmonary venous flow.
 Aim: Evaluate changes of flow parameters after transcatheter closure secundum atrial defect.
 Patients Methods: 50 patients with aged from 3.5 to 31 years were included study. Pulmonary Doppler ventricular function evaluated before successful by transthoracic transesophageal echocardiography.
 Results: The size ranged 15 37mm mean (24.96 ±7.52), Normal systolic diastolic waves replaced continuous antegrade wave (mean 60±13.6 cm/s) all patients. Post-closure, normal pattern was regained, two separate waves, decrease peak Systolic velocity (44.54±8.12 cm/sec vs 69.61±12.37, P=0.000), Diastolic Wave (55.85±9.81 72.65±10.38, P=0.000) reversal (28.75±4.63cm/sec 21.18±3.64, P=0.000). In multivariate regression analysis, predictors haemodynamic ASD size,(odds ratio 1.508, P=0.007, 95% CI 1.153,2.671) ASD/IAS (odds 2.313, P=0.001, 1.064,3.104).
 Conclusions: have characteristic pattern: predominance wave, which return closure. These could be helpful echocardiographic tool prediction defect.