Alpha-Fetoprotein: A Revolutionary Anti-Cancer Drug
نویسندگان
چکیده
Alpha-fetoprotein is an oncofetal protein the embryo produces during fetal development. The serves two critical functions simultaneously: it delivers nutrients to growing cells and immature myeloid-derived suppressor cells, so mother’s immune system doesn’t attack embryo. present in minuscule amounts adults elevated alpha-fetoprotein levels serve as pregnancy or tumor markers. Exogenous has a new application immunotherapy drug. It can deliver drugs natural shuttle manner stimulate them calm hyperactive response many physiological pathological conditions. On other hand, loaded with toxins kills unleashes killer cytotoxic lymphocytes erase cancer. Most cancers have that specifically bind alpha-fetoprotein, this targets chemotherapy also. So, combines both potent cancer targeted activities. be chemically conjugated non-covalently. Both preparations demonstrated superior efficacy safety compared alone. Alpha-fetoprotein-toxin immuno/chemotherapy not personalized. There no need preselect patients for treatments they cell levels. anti-cancer of porcine non-covalent complexes selected administered orally remarkable discovery needs research. Cancer treatment prevention are different issues, could approaches. administration effective early metastasis mifepristone pills prevention.
منابع مشابه
Characterizations of Anti-Alpha-Fetoprotein-Conjugated Magnetic Nanoparticles Associated with Alpha-Fetoprotein for Biomedical Applications
In this work, we report characterizations of biofunctionalized magnetic nanoparticles (BMNPs) associated with alpha-fetoprotein (AFP) for biomedical applications. The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-coated Fe₃O₄ labeled as Fe₃O₄-anti-AFP, and the target is AFP. We characterize magnetic properties, such as increments of magnetization ΔMH an...
متن کاملMONOCLONAL ANTIBODIES TO HUMAN ALPHA-FETOPROTEIN
Alpha-fetoprotein (AFP), a serum glycoprotein belonging to the onco-developmental proteins group, serves as a marker both in cancer research and in studies concerning fetal development and fetal pathophysiology. Monoclonal anti-AFP antibodies are essential reagents in developing appropriate techniques for measurement of this protein. In this study, in order to produce anti-AFP monoclonal a...
متن کاملA case of alpha-fetoprotein-producing gastric cancer.
INTRODUCTION A case of alpha-fetoprotein (AFP)-producing gastric cancer is described in a 57-year-old Chinese woman. CLINICAL PICTURE She presented with bleeding tendency and bone pain, and was found to have haematological evidence of disseminated intravascular coagulation and spinal metastasis. Her tumour markers, including AFP, Ca 19-9 and carcinoembryonic antigen (CEA) were elevated. In vi...
متن کاملNovel characteristics of alpha-fetoprotein (AFP)-producing gastric cancer
Background Although serum AFP level is increased in the AFP-producing gastric cancer (GC) patient, AFP-producing GC may become recurrent without re-elevation of serum AFP level. Therefore, novel characteristics of AFP-producing GC such as other biomarkers are to be explored. Results 35 AFP-GC and 48 non-AFP-GC patients were included. Our present study revealed that blood type O (15 cases, 42....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical research archives
سال: 2023
ISSN: ['2375-1916', '2375-1924']
DOI: https://doi.org/10.18103/mra.v11i7.1.4125