alpha 1-Antitrypsin and coeliac disease in spain.
نویسندگان
چکیده
منابع مشابه
a , - Antitrypsin and coeliac disease in Spain
Ninety-three Spanish children suffering from coeliac disease and 103 control subjects from the same area were screened for the amount of ao1-antitrypsin (oc1AT) and for any electrophoretic variations in it. In this case-control study no significant differences were detected either in phenotype distribution or amount. The present results indicate that no genetic association exists between a1AT a...
متن کاملAlpha-1-antitrypsin immunoreactivity in the small bowel in coeliac disease.
The role of alpha-1-antitrypsin (A1AT) in the small intestinal mucosa in health and disease is poorly understood. We studied the prevalence and distribution of A1AT positive cells in small bowel biopsies from 35 coeliac disease patients and 25 normal controls retrieved from the records of the Department of Pathology, University of Oxford. Serial 6 micron thick paraffin sections were stained wit...
متن کاملLiver disease and alpha 1-antitrypsin deficiency.
Discovery of AAT deficiency by Laurell and Eriksson in 1963 [2] provided a foundation for current thinking about the pathogenesis of pulmonary emphysema [3,4]. Although AAT deficiency has become one of the best understood genetic disorders at a molecular and protein level, many questions about the clinical disease remain unanswered. Current American and International research projects should pr...
متن کاملAssessment of Alpha-1 Antitrypsin Deficiency in Patients with Severe Chronic Obstructive Pulmonary Disease
Background and Aims: Chronic obstructive pulmonary disease (COPD) is a kind of pulmonary diseases characterized by chronic obstruction of lung that is in the form of a diffuse narrowing of airways resulting in air flow resistance. Alpha-1 antitrypsin (AAT) deficiency is genetically relatively common risk factor in patients with COPD throughout the world and the exact cause of its prevalence is ...
متن کاملAlpha- 1 Antitrypsin Deficiency in Children: Pulmonary Involvement
Introduction: α1-antitrypsin deficiency (α1-ATD) is one of the most common genetic disorders in white race, a usual cause of liver disease in children, and hepatopulmonary involvement in children and adult. The aim of this case description is presenting a child with early lung disease without liver parenchymal disorder. Case presentation: We describe a 13 year old boy because of exertional dysp...
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ژورنال
عنوان ژورنال: Gut
سال: 1980
ISSN: 0017-5749
DOI: 10.1136/gut.21.11.948