Allergen-Specific Immunotherapy for Food Allergy: Latest Advances in Vaccines
نویسندگان
چکیده
منابع مشابه
Allergen-Specific Immunotherapy for Food Allergy: Latest Advances in Vaccines
Although great progress has been made to elucidate the molecular and cellular basis of allergic disorders, it is not completely understood why some individuals develop allergic sensitization to some foods, while the majority of individuals are immunologically tolerant. In addition, it is yet not fully understood which is the molecular basis involved in the immunopathogenesis of the mechanisms e...
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While the efficacy of classical subcutaneous allergen-specific immunotherapy (ASIT) has been proven by a multitude of double-blind placebo-controlled trials for various allergens and clinical conditions such as allergic rhinoconjuncitivis, allergic bronchial asthma or insect venom anaphylaxis, patients suffering from food allergy are still left with the simple recommendation of avoidance. This ...
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since 20th century, when allergy was defined, an ongoing attempt for discovering the mechanisms underlying it and its treatment began. defining allergens as well as cells such as regulatory t-cells and characterizing the antibodies involved in the pathogenesis (including blocking antibodies) have helped very much towards a better understanding of the immunologic process.however, allergen speci...
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Specific immunotherapy (SIT) protocols for nutritional allergens have only recently been established with a focus on oral allergy syndrome because of pollen cross-reacting antibodies. For these patients, a substantial number of studies have been published suggesting benefits from SIT. The situation in true anaphylaxis to food allergens such as peanut allergy is more complex, and therapeutic str...
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Allergen-specific IgG antibodies play a significant role in allergen-specific tolerance, either naturally induced or generated by specific immunotherapy. Nevertheless, the underlying mechanisms are still debated, and allergen-specific IgG determinations are not recommended as a diagnostic tool in IgE-mediated allergy. This review summarizes the latest findings on the immunological and diagnosti...
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ژورنال
عنوان ژورنال: International Journal of Vaccines & Vaccination
سال: 2016
ISSN: 2470-9980
DOI: 10.15406/ijvv.2016.03.00059