Allelic polymorphism of emm loci provides evidence for horizontal gene spread in group A streptococci.
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چکیده
منابع مشابه
Allelic polymorphism of emm loci provides evidence for horizontal gene spread in group A streptococci.
Group A streptococci have a virulence regulon containing a single emm locus or two or three distinct and adjacent loci of structurally related emm family genes. The products of the emm gene cluster consist of fibrillar surface proteins, at least some of which are known to contain determinants of type specificity located in their NH2-terminal regions, lying distal to the cell surface. The emm ge...
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In group A streptococci, genetic markers for principal tissue reservoir are located within emm genes, which encode surface proteins that have a role in virulence. A worldwide collection of 160 isolates was evaluated for two traits: chromosomal emm gene markers for tissue tropism (designated patterns A-E), and bacteriophage-associated genes (speA and speC) encoding pyrogenic exotoxins. The speA ...
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4. Fantin B, Pangon B, Potel G, Caron F, Vallee E, Vallois JM, et al. Activity of sulbactam in combination with ceftriaxone in vitro and in experimental endocarditis caused by Escherichia coli producing SHV-2-like betalactamases. Antimicrob Agents Chemother 1990:34;581-6. 5. Morosini MI, Blasquez J, Negri MC, Canton R, Loza E, Baquero F. Characterization of a nosocomial outbreak involving an ep...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1994
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.91.8.3280