Allele-specific methylation of type 1 diabetes susceptibility genes
نویسندگان
چکیده
منابع مشابه
The Type 1 Diabetes - HLA Susceptibility Interactome - Identification of HLA Genotype-Specific Disease Genes for Type 1 Diabetes
BACKGROUND The individual contribution of genes in the HLA region to the risk of developing type 1 diabetes (T1D) is confounded by the high linkage disequilibrium (LD) in this region. Using a novel approach we have combined genetic association data with information on functional protein-protein interactions to elucidate risk independent of LD and to place the genetic association into a function...
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ژورنال
عنوان ژورنال: Journal of Autoimmunity
سال: 2018
ISSN: 0896-8411
DOI: 10.1016/j.jaut.2017.11.008