Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length

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Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length

Alkylcyanoacrylate particles were physico-chemically characterized in terms of size, surface charge, zeta potential, interaction with charged serum components and surface hydrophobicity as relevant parameters influencing the in vitro interaction with cells in culture and the in vivo organ distribution and fate after intravenous administration. Methyl-, ethyl-, isobutyland isohexylcyanoacrylate ...

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ژورنال

عنوان ژورنال: International Journal of Pharmaceutics

سال: 1992

ISSN: 0378-5173

DOI: 10.1016/0378-5173(92)90209-k