Alkaloids from Psychotria Target Sirtuins: In Silico and In Vitro Interaction Studies
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چکیده
منابع مشابه
In vitro antioxidant activity of alkaloids from southern Brazilian Psychotria: a comparative analysis
Background Monoterpene índole alkaloids (MIAs) comprise a class of secondary metabolites of dual biosynthetic origin, characterized by the presence of an indole and a terpene portion. MIAs are widely studied because of their bioactive properties and pharmacological potential. In this study, major MIAs from native species of Psychotria of southern Brazil were used: P. brachyceras, P. umbellata a...
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Objective(s):This study aims at exploring cytotoxic activity of different peptides derived from VSVG protein against MCF-7 and MDA-MB-231 breast cancer cell lines and human embryonic kidney normal cell (HEK 293). Materials and Methods: The ANTICP web server was used to predict anticancer peptides. The cytotoxic activity of peptides with high score (P26, P7) and low score (P19) was examined b...
متن کاملBioactive Alkaloids from South American Psychotria and Related Species
Many important molecules have been discovered from tropical and sub-tropical plant biodiversity. However, the largest part of the chemical profile of such biodiversity remains unknown. Combining ethnopharmacological and chemotaxonomical investigation can be a good strategy in bioactive compound discovery. South American Psychotria species studied by this approach proved to be a rich source of n...
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با به کار گیری روش گفتما ن شنا سی در تحقیق حا ضر گفتا ر میا ن آموزگا را ن و زبا ن آموزا ن در کلا سهای زبا ن انگلیسی در ایرا ن مورد بررسی قرار گرفت. ا هداف تحقیق عبا رت بودند از: الف) شنا سا ئی سا ختارهای ارتبا ط گفتا ری میا ن معلمین و زبا ن آموزا ن ب) بررسی تا ثیر نقش جنسیت دبیرا ن و زبا ن آموزان بر سا ختا رهای ارتبا ط گفتا ری میا ن آنها پ) مشخص کردن اینکه آ یا آموزگاران غا لب بر این ارتبا ط گف...
Absence of alkaloids in Psychotria carthagenensis Jacq. (Rubiaceae).
Psychotria viridis and P. carthagenensis are often discussed in relation to the hallucinogenic beverage Ayahuasca, used for religious, medicinal and social purposes. The significance of including Psychotria species in this beverage has been understood on the basis of substantial amounts of tryptamine alkaloids detected on leaves of both P. viridis and P. carthagenensis. Nevertheless, there is a...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2014
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0034-1383261