Alcohol-oxidizing enzymes in 13 Drosophila species

Hepatic Microsomal Alcohol-oxidizing System

Oxidation of methanol, ethanol, propanol, and butanol by the microsomal fraction of rat liver homogenate is described. This microsomal alcohol-oxidizing system is dependent on NADPH and molecular oxygen and is partially inhibited by CO, features which are commori for microsomal drug-metabolizing enzymes. The activity of the microsomal alcohol-oxidizing system could be dissociated from the alcoh...

Alcohol algorithm: 09/18/13 Alcohol Algorithm

Hydrogen Bond Control of Active Oxidizing Species in Manganese Porphyrin Hydroxylation Catalysts

Some meso-tetra aryl porphyrinato manganese (III) acetate or chloride complexes including meso-tetraphenyl porphyrinato manganese (III) chloride (TPPMnCl), meso-tetrakis(2,3-dimethoxyphenyl)porphyrinato manganese(III) acetate, (T(2,3-OMeP)PMnOAc) and meso-tetrakis(pentaflourophenyl)porphyrinato manganese (III) acetate (TPFPPMnOAc) were synthesized. These porphyrins were used as catalyst in the ...

Drosophila alcohol dehydrogenase polymorphism and carbon-13 fluxes: opportunities for epistasis and natural selection.

The influence of genetic variations in Drosophila alcohol dehydrogenase (ADH) on steady-state metabolic fluxes was studied by means of 13C NMR spectroscopy. Four pathways were found to be operative during 8 hr of ethanol degradation in third instar larvae of Drosophila. Seven strains differed by 18-25% in the ratio between two major pathway fluxes, i.e., into glutamate-glutamine-proline vs. lac...

Digestive Enzymes in Marine Species

The proteolytic activities of the digestive tract of three carnivorous fish species (Sebastes mentella, Scophthalmus maximus, Sparus aurata) have been studied. The activity found in the stomach showed a pH optimum of 2.0 for all species, whereas this was in the alkaline range (9.5-10.0) in the intestinal extracts. Similar optimal temperature was measured for all species, although higher residua...