Albocycline: structure determination by X-ray crystallography.

Albocycline: structure determination by x-ray crystallography.

The structure and absolute configuration of the macrolide antibiotic albocycline (1a) has been determined by X-ray crystallographic analysis on the derived p-bromobenzoate (1b). The absolute configuration of albocycline is 4R, 7S, 12S, 13R.

Multiple challenges in protein structure determination by x-ray crystallography

Structure determination of a human virus by the combination of cryo-EM and X-ray crystallography

Virus 3D atomic structures provide insight into our understanding of viral life cycles and the development of antiviral drugs. X-ray crystallography and cryo-EM have been used to determine the atomic structure of viruses. However, limited availability of biological samples, biosafety issues due to virus infection, and sometimes inherent characteristics of viruses, pose difficulties on combining...

Structure Determination of Natural Epoxycyclopentanes by X - ray Crystallography and NMR Spectroscopy '

of the phosphorus-oxygen bond renders reduction irreversible. Because trialkylphosphines are kinetically stable in aqueous solution, selective for the reduction of the disulfide linkage, and unreactive toward many other functional groups, they are attractive as reducing agents in biochemical systems. Their utility has been limited by the low solubility of most simple trialkylphosphines in water...

The X-ray Transform and its Application in Nano Crystallography

In this article a review on the definition of the X- ray transform and some ofits applications in Nano crystallography is presented. We shall show that the X- raytransform is a special case of the Radon transform on homogeneous spaces when thetopological group E(n)- the Euclidean group - acts on ℝ2 transitively. First someproperties of the Radon transform are investigated then the relationship ...