Air Pollution and Inflammation (Interleukin-6, C-Reactive Protein, Fibrinogen) in Myocardial Infarction Survivors
نویسندگان
چکیده
منابع مشابه
Air Pollution and Inflammation (Interleukin-6, C-Reactive Protein, Fibrinogen) in Myocardial Infarction Survivors
BACKGROUND Numerous studies have found that ambient air pollution has been associated with cardiovascular disease exacerbation. OBJECTIVES Given previous findings, we hypothesized that particulate air pollution might induce systemic inflammation in myocardial infarction (MI) survivors, contributing to an increased vulnerability to elevated concentrations of ambient particles. METHODS A pros...
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T he initiation of atherosclerosis and its progression to an acute coronary syndrome (ACS) are intricate processes with many factors, but one central factor is inflammation. Interleukin-6 is a proinflammatory cytokine that may have a role in the initiation, progression, and vulnerability of atherosclerotic lesions. Interleukin-6 works upstream of CRP (C-reactive protein) and downstream of inter...
متن کاملair pollution and myocardial infarction
coronary artery disease is one of the main causes of mortality in most developed countries. there is also an increasing rate of mortality in developing countries where in addition to coronary artery disease, infection diseases still not have been controlled. although, now a day coronary artery disease is responsible for half of deaths in developed countries, this regrettable event is increasing...
متن کاملModification of the Interleukin-6 Response to Air Pollution by Interleukin-6 and Fibrinogen Polymorphisms
BACKGROUND Evidence suggests that cardiovascular effects of air pollution are mediated by inflammation and that air pollution can induce genetic expression of the interleukin-6 gene (IL6). OBJECTIVES We investigated whether IL6 and fibrinogen gene variants can affect plasma IL-6 responses to air pollution in patients with cardiovascular disease. METHODS We repeatedly determined plasma IL-6 ...
متن کاملAltered Cardiac Repolarization in Association with Air Pollution and Air Temperature among Myocardial Infarction Survivors
BACKGROUND Epidemiological studies have shown that ambient particulate matter (PM) and changes in air temperature are associated with increased cardiopulmonary events. OBJECTIVE We hypothesized that patients with previous myocardial infarction (MI) experience changes in heart rate (HR) and repolarization parameters, such as Bazett-corrected QT interval (QTc), and T-wave amplitude (Tamp), in a...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2007
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.10021